• A type of cell that makes neurohormones (chemicals that are made by nerve cells and used to send signals to other cells) and releases them into the blood. Chromaffin cells make epinephrine (adrenaline) and norepinephrine (noradrenaline). They are found in the adrenal glands or in groups of nerve cells called ganglia.
  NCI Dictionary of Cancer Terms
  U.S. National Cancer Institute, 2021
• Located in the medulla of adrenal gland and paraganglia; can discharge epinephrine into bloodstream upon stimulation and through this the sympathetic nervous system can mediate hormonal-type actions on various organs throughout the body.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Neuroendocrine cells, found in the medulla of the adrenal gland and other sympathetic nervous system ganglia, that release catecholamines into circulation.
  NCI
  U.S. National Cancer Institute, 2021
• Cells that store epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia (PARAGANGLIA, CHROMAFFIN) of the sympathetic nervous system.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025