Disease or Syndrome
chronic fatigue syndrome

chron·ic fa·tigue syn·drome [ krah-nik fuh-teeg sin-drome ]
Subclass of:
Neuromuscular Diseases;
Encephalomyelitis;
Chronic disease;
Virus Diseases;
Myopathy
Also called:
CFS; ME/CFS; Myalgic Encephalomyelitis; SEID; Systemic Exertion Intolerance Disease
Definitions related to chronic fatigue syndrome:
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A condition lasting for more than 6 months in which a person feels tired most of the time and may have trouble concentrating and carrying out daily activities. Other symptoms include sore throat, fever, muscle weakness, headache, and joint pain.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A disorder of ongoing, severe tiredness that interferes with a person's ability to function well, isn't improved with rest, and isn't caused by another illness.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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A syndrome of unknown etiology. Chronic fatigue syndrome (CFS) is a clinical diagnosis characterized by an unexplained persistent or relapsing chronic fatigue that is of at least six months' duration, is not the result of ongoing exertion, is not substantially alleviated by rest, and results in substantial reduction of previous levels of occupational, educational, social, or personal activities. Common concurrent symptoms of at least six months duration include impairment of memory or concentration, diffuse pain, sore throat, tender lymph nodes, headaches of a new type, pattern, or severity, and nonrestorative sleep. The etiology of CFS may be viral or immunologic. Neurasthenia and fibromyalgia may represent related disorders. Also known as myalgic encephalomyelitis.NCI ThesaurusU.S. National Cancer Institute, 2021
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Distinctive syndrome characterized by chronic fatigue, mild fever, lymphadenopathy, headache, myalgia, arthralgia, depression, and memory loss; candidate etiologic agents include Epstein-Barr and other herpesviruses.CRISP ThesaurusNational Institutes of Health, 2006
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Chronic fatigue syndrome (CFS) is a serious, long-term illness that affects many body systems. Another name for it is myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). CFS can often make you unable to do your usual activities. Sometimes you may not even be able to get out of bed. The cause of CFS is unknown. There may be more than one thing that causes it. It is possible that two or more triggers might work together to cause the illness. Anyone can get CFS, but it is most common in people between 40 and 60 years old. Adult women have it more often that adult men. Whites are more likely than other races to get a diagnosis of CFS, but many people with CFS have not been diagnosed with it. CFS symptoms can include Severe fatigue that is not improved by rest; Sleep problems; Post-exertional malaise (PEM), where your symptoms get worse after any physical or mental activity; Problems with thinking and concentrating; Pain; Dizziness. CFS can be unpredictable. Your symptoms may come and go. They may change over time - sometimes they might get better, and other times they may get worse. CFS can be difficult to diagnose. There is...MedlinePlusU.S. National Library of Medicine, 2021
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(fatigue syndrome, chronic) A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Chronic fatigue syndrome (CFS, also called myalgic encephalomyelitis/chronic fatigue syndrome [ME/CFS]) is a syndrome of life-altering fatigue lasting > 6 months that is unexplained and is accompanied by a number of associated symptoms. Management includes validating the patient's disability, treating specific symptoms, and in some...Merck & Co., Inc., 2020
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Chronic fatigue syndrome (CFS) is a disorder characterized by a state of chronic fatigue that persists for more than 6 months, has no clear cause, and is accompanied by cognitive difficulties. CSF was initially termed encephalomyalgia (or myalgic encephalomyelitis) because British clinicians noted that the essential clinical features of...WebMD, 2019
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Chronic fatigue syndrome (CFS) is a complicated disorder characterized by extreme fatigue that lasts for at least six months and that can't be fully explained by an underlying medical condition. The fatigue worsens with physical or mental activity, but doesn't improve with rest.Mayo Foundation for Medical Education and Research
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Definitions of chronic fatigue syndrome (CFS) have evolved from a focus on fatigue and impairment as described in the Centers for Disease Control (CDC) criteria, to postexertional malaise (PEM)/exertional exhaustion in myalgic encephalomyelitis (ME)/CFS as defined by the Canadian Consensus Criteria, and systemic exertion intolerance...Athenahealth, Inc., 2019
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Chronic fatigue syndrome (CFS), disorder characterized by persistent debilitating fatigue. There exist two specific criteria that must be met for a diagnosis of CFS: (1) severe fatigue lasting six months or longer and (2) the coexistence of any four of a number of characteristic symptoms, defined...Encyclopedia Britannica, Inc., 2020
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