Biologically Active Substance
citrulline
cit·rul·line [ si-truh-leen ]
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Definitions related to citrulline:
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A non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product.NCI ThesaurusU.S. National Cancer Institute, 2021
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Amino acid, C6H13N3O3, originally isolated from watermelon, that is produced as an intermediate in the conversion of ornithine to arginine during urea formation in the liver; chemical name L-ornithine, N5-(aminocarbonyl).CRISP ThesaurusNational Institutes of Health, 2006
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