Pharmacologic Substance
cromolyn
Brand Names:
Gastrocrom; Nasalcrom
Effect:
Decreased Histamine Activity; Decreased Histamine Release; Decreased Leukotriene Activity
May Prevent:
Asthma, Exercise-Induced
May Treat:
Asthma; Bronchial Spasm; Conjunctivitis; Food Hypersensitivity; Inflammatory Bowel Diseases; Mastocytosis; Rhinitis, Allergic, Perennial
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to cromolyn:
  • A synthetic mast cell stabilizer with anti-inflammatory activity. Cromolyn probably interferes with the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in type I allergic reactions. Cromolyn also prevents inflammatory mediator release from eosinophils.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Chromone complex which blocks mast cell degeneration; primarily used as an antiasthmatic; also an orphan drug for the treatment of mastocytosis and vernal keratoconjunctivitis.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.