Disease or Syndrome
cutis laxa
Subclass of:
Connective Tissue Diseases;
Skin Diseases, Genetic
Definitions related to cutis laxa:
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A congenital or acquired disorder affecting the elastic fibers of the skin. It is characterized by loss of elasticity resulting in loosening and folding of the skin.NCI ThesaurusU.S. National Cancer Institute, 2021
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A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation. Cutis laxa is usually a genetic disease, but acquired cases have been reported. (From Dorland, 27th ed)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Cutis laxa (CL) is an inherited or acquired connective tissue disorder characterized by wrinkled, redundant and sagging inelastic skin associated with skeletal and developmental anomalies and, in some cases, with severe systemic involvement. Several different forms of inherited CL have been described, differentiated on the basis of the mode of inheritance and differences in the extent of internal organ involvement, associated anomalies and disease severity.OrphaNetINSERM, 2021
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Group of connective tissue diseases in which skin hangs in loose pendulous folds; believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation; usually a genetic disease, but acquired cases have been reported.CRISP ThesaurusNational Institutes of Health, 2006
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Wrinkled, redundant, inelastic and sagging skin.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Cutis laxa is characterized by lax skin hanging in loose folds. Diagnosis is clinical. There is no specific treatment, but plastic surgery is sometimes done.Merck & Co., Inc., 2020
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Cutis laxa is a connective tissue disorder characterized by skin that is sagging and not stretchy. The skin often hangs in loose folds, causing the face and other parts of the body to have a droopy appearance. Cutis laxa can also affect connective tissue in other parts of the body, including the heart, blood vessels, joints, intestines,...National Center for Advancing Translational Sciences
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Cutis laxa, rare disorder in which the skin hangs in loose folds. The cause of cutis laxa is unknown, but the defect appears to be an abnormality in the formation or structure of the protein elastin, the principal component of the elastic connective tissues of the skin; as a result, degenerative...Encyclopedia Britannica, Inc., 2020
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