Immunologic Factor
daclizumab
[ duh-klih-zoo-mab ]
Effect:
Decreased Cytokine Activity; Decreased Lymphocyte Activation; Decreased Lymphocyte Cell Production
May Prevent:
Graft vs Host Disease
May Treat:
Graft vs Host Disease;
Multiple Sclerosis
Definitions related to daclizumab:
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A monoclonal antibody that is being studied in the treatment of adult T-cell leukemia and in the treatment of cytopenia (low blood cell count).NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A recombinant monoclonal antibody interleukin-2 receptor antagonist. Daclizumab binds specifically to the alpha subunit of the human interleukin-2 (IL-2) receptor expressed on the surface of activated lymphocytes in vivo, thereby inhibiting IL-2 binding and IL-2-mediated lymphocyte activation, a critical cellular immune response pathway.NCI ThesaurusU.S. National Cancer Institute, 2021
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An anti-TAC (INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT) humanized monoclonal antibody (immunoglobulin G1 disulfide with human-mouse monoclonal clone 1H4 light chain, dimer) that is used in the treatment of ACUTE RELAPSING MULTIPLE SCLEROSIS.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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