Antibiotic
demeclocycline
[ dem-uh-kloh-sahy-kleen ]
Brand Names:
Declomycin
Effect:
Cell Membrane Alteration; Decreased Mitosis; Decreased Protein Synthesis
May Treat:
Acne Vulgaris;
Actinomycosis;
Campylobacter Infections;
Cholera;
Clostridium Infections;
Gonorrhea;
Inappropriate ADH Syndrome;
Lymphogranuloma Venereum;
Plague;
Pneumonia, Mycoplasma;
Psittacosis;
Rocky Mountain Spotted Fever;
Trachoma;
Typhoid Fever;
Urinary Tract Infections;
Whooping Cough
More Information:
Definitions related to demeclocycline:
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A semi-synthetic, broad-spectrum naphthacene antibiotic produced by the bacterium Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal tubules, thereby causing diuresis.NCI ThesaurusU.S. National Cancer Institute, 2021
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A TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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