Neoplastic Process
desmoplastic fibroma
Subclass of:
fibroma
Definitions related to desmoplastic fibroma:
  • (osteofibroma, benign) A benign neoplasm characterized by osteolysis and the presence of a rich collagenous stroma and spindle cells.
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • A rare, benign, locally aggressive osteolytic neoplasm. It is characterized by the presence of a rich collagenous stroma and spindle cells with minimal cellular atypia.
    NCI
    U.S. National Cancer Institute, 2021
  • (fibroma, desmoplastic) An extremely rare bone tumor characterized by abundant collagen formation and a fibrous stroma, without evidence of mitosis or pleomorphism. It appears on x-rays as an osteolytic lesion with well-defined margins and must be differentiated from primary fibrosarcoma of bone. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1441)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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