Disease or Syndrome
dupuytren contracture
Subclass of:
Connective Tissue Diseases;
Contracture;
fibroma
Also called:
Palmar Fibromatosis
Definitions related to dupuytren contracture:
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(palmar fibromatosis) A superficial fibromatosis arising from the soft tissue of the palm. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It predominantly affects adult males.NCI ThesaurusU.S. National Cancer Institute, 2021
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A fibromatosis of the palmar fascia characterized by thickening and contracture of the fibrous bands on the palmar surfaces of the hand and fingers. It arises most commonly in men between the ages of 30 and 50.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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An abnormality of the hand resulting from contracture of the palmar fascia with a fixed flexion deformity of the metacarpophalangeal (MCP) joints and the proximal interphalangeal (PIP) joints.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Dupuytren contracture is progressive contracture of the palmar fascial bands, causing flexion deformities of the fingers. Treatment is with corticosteroid injection, surgery, or injections of clostridial collagenase.Merck & Co., Inc., 2020
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Frequency United States Dupuytren disease is common in the United States with a prevalence of 4%, reflecting immigration from Northern Europe. International In Northern Europe the prevalence ranges from 4-39%.WebMD, 2019
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Dupuytren's (du-pwe-TRANZ) contracture is a hand deformity that usually develops over years. The condition affects a layer of tissue that lies under the skin of your palm. Knots of tissue form under the skin - eventually creating a thick cord that can pull one or more fingers into a bent position.Mayo Foundation for Medical Education and Research
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An inherited disease of progressive fibrous tissue contracture of the palmar fascia, Dupuytren contracture is seen predominantly in men of northern European descent aged >40 years. Its inheritance pattern is believed to be autosomal dominant with variable penetrance.Athenahealth, Inc., 2019
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Dupuytren's contracture, flexion deformity of the hands caused by thickening of the fascia, or fibrous connective tissue, of the palm. The proliferation of connective tissue causes the tendons of one or more fingers to shorten and tighten, leaving the finger permanently flexed. Disability may be...Encyclopedia Britannica, Inc., 2020
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