Pharmacologic Substance
desvenlafaxine succinate
Effect:
Increased Central Nervous System Norepinephrine Activity; Increased Central Nervous System Serotonin Activity
May Treat:
Depressive Disorder, Major
More Information:
ChemID; DailyMed; PDR
Definitions related to desvenlafaxine succinate:
  • A cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • The succinate salt form of desvenlafaxine, a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state.
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.