Pharmacologic Substance
propofol
Brand Names:
Diprivan; Propoflo; Propoven
Effect:
Decreased Central Nervous System Disorganized Electrical Activity; Decreased CNS Organized Electrical Activity; Decreased Peripheral Nervous System Organized Electrical Activity; General Anesthesia
May Prevent:
Pain; Postoperative Nausea and Vomiting
May Treat:
Delirium; Pain; Psychomotor Agitation; Status Epilepticus
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to propofol:
  • A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). This agent is associated with minimal respiratory depression and has a short half-life with a duration of action of 2 to 10 minutes.
    NCI
    U.S. National Cancer Institute, 2021
  • An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Propofol, anesthetic drug used to induce and maintain general anesthesia and to sedate patients for certain medical procedures. Propofol was first tested clinically in 1977. When administered by intravenous injection, it quickly induced anesthesia, with fast and smooth recovery afterward. Animal...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2025
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