Pharmacologic Substance
didanosine Audio
[ dy-da-noh-seen ]
Brand Names:
Videx; Videx EC
Effect:
Decreased Reverse Transcription to DNA
May Treat:
Acquired Immunodeficiency Syndrome
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to didanosine:
  • A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A drug used to treat infection caused by viruses.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A nucleoside reverse transcriptase inhibitor analog of adenosine.
    NCI
    U.S. National Cancer Institute, 2021
  • (2'3' dideoxyinosine) Inosine nucleoside analog; antiHIV agent.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.