Pharmacologic Substance
dimenhydrinate
[ dahy-men-hahy-druh-neyt ]
Brand Names:
Airmit; Dramamine; Driminate; TripTone; Wal-Dram
Effect:
Decreased Histamine Activity
May Prevent:
Nausea; Vertigo; Vomiting
May Treat:
Motion Sickness; Nausea; Vertigo; Vomiting
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to dimenhydrinate:
  • A drug combination that contains diphenhydramine and theophylline. It is used for treating VERTIGO, MOTION SICKNESS, and NAUSEA associated with PREGNANCY.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • An ethanolamine and first-generation histamine antagonist with anti-allergic activity. Dimenhydrinate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, GI smooth muscle spasm.
    NCI
    U.S. National Cancer Institute, 2021
  • Dimenhydrinate, antihistamine used to treat nausea, chiefly that which occurs in motion sickness, and also in the symptomatic treatment of vertigo, such as in Meniere syndrome, a disease of the inner ear. Dimenhydrinate, a synthetic drug introduced into medicine in 1949, is administered orally in...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2025
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