Pharmacologic Substance
doxapram
Brand Names:
Dopram
Effect:
Increased Medullary Respiratory Drive; Increased Organized Electrical Activity
May Prevent:
Respiratory Insufficiency
May Treat:
Hypercapnia; Respiratory Hypersensitivity; Substance-Related Disorders
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to doxapram:
  • A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A respiratory stimulant with analeptic activity. Doxapram, independent of oxygen levels, directly stimulates the peripheral carotid chemoreceptors, possibly by inhibiting the potassium channels of type I cells within the carotid body, thereby stimulating catecholamines release. This results in the prevention or reversal of both narcotic- and CNS depressant-induced respiratory depression.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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