Pharmacologic Substance
doxapram
Brand Names:
Dopram
Effect:
Increased Medullary Respiratory Drive; Increased Organized Electrical Activity
May Prevent:
Respiratory Insufficiency
May Treat:
Hypercapnia;
Respiratory Hypersensitivity;
Substance-Related Disorders
More Information:
Definitions related to doxapram:
-
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
-
A respiratory stimulant with analeptic activity. Doxapram, independent of oxygen levels, directly stimulates the peripheral carotid chemoreceptors, possibly by inhibiting the potassium channels of type I cells within the carotid body, thereby stimulating catecholamines release. This results in the prevention or reversal of both narcotic- and CNS depressant-induced respiratory depression.NCI ThesaurusU.S. National Cancer Institute, 2021
Return to OpenMD Medical Dictionary
> D
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.