Pharmacologic Substance
raltegravir potassium
Effect:
Decreased DNA Integrity
May Treat:
HIV Infections
More Information:
ChemID; DailyMed; PDR
Definitions related to raltegravir potassium:
  • A pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • The orally bioavailable potassium salt of a human immunodeficiency virus (HIV) integrase strand transfer inhibitor (HIV-1 INSTI) with HIV-1 antiviral activity. Raltegravir binds to and inhibits integrase, an HIV enzyme that inserts viral genetic material into the genetic material of the infected human cell. Inhibition of integrase prevents insertion of HIV DNA into the human DNA genome, thus blocking HIV replication.
    NCI
    U.S. National Cancer Institute, 2021
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