Biologically Active Substance
dystrophin
dys·tro·phin
Subclass of:
Cytoskeletal Proteins;
Membrane Proteins;
Muscle Proteins
Definitions related to dystrophin:
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A muscle protein localized in surface membranes which is the product of the Duchenne/Becker muscular dystrophy gene. Individuals with Duchenne muscular dystrophy usually lack dystrophin completely while those with Becker muscular dystrophy have dystrophin of an altered size. It shares features with other cytoskeletal proteins such as SPECTRIN and alpha-actinin but the precise function of dystrophin is not clear. One possible role might be to preserve the integrity and alignment of the plasma membrane to the myofibrils during muscle contraction and relaxation. MW 400 kDa.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Large, structural, spectrin-like protein expressed in skeletal muscle; genetic defect is linked to Duchenne and Becker muscular dystrophy.CRISP ThesaurusNational Institutes of Health, 2006
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