Pharmacologic Substance
echothiophate iodide
Effect:
Decreased Intraocular Fluid Pressure; Increased Acetylcholine Activity; Pupillary Constriction
May Treat:
Esotropia;
Glaucoma;
Glaucoma, Angle-Closure;
Glaucoma, Open-Angle
More Information:
Definitions related to echothiophate iodide:
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A potent, long-acting cholinesterase inhibitor used as a miotic in the treatment of glaucoma.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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The iodide salt form of echothiophate, a long-acting cholinesterase inhibitor with parasympathomimetic activity. Echothiophate iodide potentiates the action of endogenous acetylcholine by inhibiting acetylcholinesterase that hydrolyzes acetylcholine. When applied topically to the eye, this agent prolongs stimulation of the parasympathetic receptors at the neuromuscular junctions of the longitudinal muscle of the ciliary body. Contraction of longitudinal muscle pulls on the scleral spur, and opens the trabecular meshwork, thereby increases aqueous humor outflow from the eye and reduces intraocular pressure.NCI ThesaurusU.S. National Cancer Institute, 2021
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