Pharmacologic Substance
edotecarin

[ eh-doh-teh-kar-in ]
Definitions related to edotecarin:
-
A substance being studied in the treatment of cancer. It is a type of topoisomerase I inhibitor.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
-
A synthetic indolocarbazole with antineoplastic activity. Edotecarin inhibits the enzyme topoisomerase I through stabilization of the DNA-enzyme complex and enhanced single-strand DNA cleavage, resulting in inhibition of DNA replication and decreased tumor cell proliferation. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
Return to OpenMD Medical Dictionary
> E
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.