Pharmacologic Substance
efaproxiral
[ eh-fuh-prok-sih-rul ]
Definitions related to efaproxiral:
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A drug that may increase the effectiveness of radiation therapy.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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