Pharmacologic Substance
emtricitabine
Brand Names:
Atripla; Biktarvy; Complera; Descovy; Emtriva; Genvoya; Odefsey; Stribild; Symtuza; Truvada
Effect:
Decreased Reverse Transcription to DNA
May Treat:
HIV Infections
More Information:
Definitions related to emtricitabine:
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A deoxycytidine analog and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B viruses. It is used to treat HIV INFECTIONS.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate within the cell. This metabolite inhibits the activity of human immunodeficiency virus (HIV) reverse transcriptase both by competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack of the essential 3'-OH group).NCI ThesaurusU.S. National Cancer Institute, 2021
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