Pharmacologic Substance
enoxaparin
[ ee-nok-suh-payr-in ]
Brand Names:
Lovenox
Effect:
Decreased Coagulation Factor Activity
May Prevent:
Angina, Unstable; Postoperative Complications; Pulmonary Embolism; Thromboembolism; Venous Thrombosis
May Treat:
Angina, Unstable;
Myocardial Infarction;
Postoperative Complications;
Pulmonary Embolism;
Thromboembolism;
Thrombophlebitis
More Information:
Definitions related to enoxaparin:
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A drug used to prevent blood clots. It belongs to the family of drugs called anticoagulants.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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