Pharmacologic Substance
epothilon
Subclass of:
Macrolides
Definitions related to epothilones:
  • (epothilon) Phytogenic antineoplastic agent; 16 membered macrolide.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • A substance obtained from bacteria that interferes with cell division. Some epothilones are being studied as treatments for cancer.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • (epothilone compound) A class of compounds isolated from the myxobacterium Sorangium cellulosum. Similar to taxanes, epothilone compounds induce microtubule polymerization and stabilize microtubules against depolymerization conditions, thereby inhibiting mitosis. (NCI)
    NCI
    U.S. National Cancer Institute, 2021
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