• (esophageal cancer) Cancer that forms in tissues lining the esophagus (the muscular tube through which food passes from the throat to the stomach). Two types of esophageal cancer are squamous cell carcinoma (cancer that begins in flat cells lining the esophagus) and adenocarcinoma (cancer that begins in cells that make and release mucus and other fluids).
  NCI Dictionary of Cancer Terms
  U.S. National Cancer Institute, 2021
• A malignant epithelial tumor arising from the esophageal mucosa. Two major histologic types of esophageal carcinoma have been described: squamous cell carcinoma and adenocarcinoma. This type of cancer is associated with excessive ethanol and cigarette usage.
  NCI
  U.S. National Cancer Institute, 2021
• The presence of a carcinoma of the esophagus.
  Human Phenotype Ontology (HPO)
  The Human Phenotype Ontology Project, 2025
• The most common malignant tumor in the proximal two thirds of the esophagus is squamous cell carcinoma; adenocarcinoma is the most common in the distal one third. Symptoms are progressive dysphagia and weight loss. Diagnosis is by endoscopy, followed by CT and endoscopic ultrasound for staging. Treatment varies with stage and generally...
  Merck Manuals
  Merck & Co., Inc., 2025