Pharmacologic Substance
estrogen inhibitor
es·tro·gen in·hib·i·tor [ es-truh-juhn in-hib-i-ter ]
Subclass of:
Hormone Antagonists
Definitions related to estrogen antagonists:
  • (antiestrogen) A substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex characteristics, the menstrual cycle, and pregnancy). Estrogen blockers may stop some cancer cells from growing and are used to prevent and treat breast cancer. They are also being studied in the treatment of other types of cancer. An estrogen blocker is a type of hormone antagonist.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • (antiestrogen) Substances that inhibit or antagonize the biosynthesis or biologic effects of estrogens by either antagonizing the responsiveness of estrogen sensitive tissues or competing with their binding sites.
    NCI
    U.S. National Cancer Institute, 2021
  • (estrogen inhibitor) Substances or agents which suppress, prevent or oppose the action of estrogen.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Antiestrogen, any substance that blocks the synthesis or action of the hormone estrogen. Estrogen can be both a beneficial and a harmful hormone. It maintains skeletal strength by preventing the loss of bone and enhancing calcium retention. However, estrogen causes the proliferation of cells in the...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2025
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