Pharmacologic Substance
ethosuximide
[ eth-oh-suhk-suh-mahyd ]
Brand Names:
Zarontin
Effect:
Neurotransmitter & Neuromuscular Transmitter Activity Alteration
May Treat:
Epilepsy, Absence
More Information:
Definitions related to ethosuximide:
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A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures.NCI ThesaurusU.S. National Cancer Institute, 2021
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An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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