Pharmacologic Substance
etodolac
Brand Names:
Lodine
Effect:
Decreased Prostaglandin Production
May Treat:
Arthritis, Rheumatoid;
Osteoarthritis;
Pain
More Information:
Definitions related to etodolac:
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A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A pyranocarboxylic acid and non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic activities. Etodolac inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. It also inhibits platelet aggregation by blocking platelet cyclooxygenase and the subsequent formation of thromboxane A2.NCI ThesaurusU.S. National Cancer Institute, 2021
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