• (erythroderma) A generalized inflammatory cutaneous disorder characterized by erythema and desquamation.
  NCI
  U.S. National Cancer Institute, 2021
• (erythroderma) An inflammatory exfoliative dermatosis involving nearly all of the surface of the skin. Erythroderma develops suddenly. A patchy erythema may generalize and spread to affect most of the skin. Scaling may appear in 2-6 days and be accompanied by hot, red, dry skin, malaise, and fever.
  Human Phenotype Ontology (HPO)
  The Human Phenotype Ontology Project, 2025
• Widespread involvement of the skin by a scaly, erythematous dermatitis occurring either as a secondary or reactive process to an underlying cutaneous disorder (e.g., atopic dermatitis, psoriasis, etc.), or as a primary or idiopathic disease; often associated with the loss of hair and nails, hyperkeratosis of the palms and soles, and pruritus.
  CRISP Thesaurus
  National Institutes of Health, 2006
• (dermatitis, exfoliative) The widespread involvement of the skin by a scaly, erythematous dermatitis occurring either as a secondary or reactive process to an underlying cutaneous disorder (e.g., atopic dermatitis, psoriasis, etc.), or as a primary or idiopathic disease. It is often associated with the loss of hair and nails, hyperkeratosis of the palms and soles, and pruritus. (From Dorland, 27th ed)
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025
• (erythroderma) A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process involves > 90% of the body surface area.
  Common Terminology Criteria for Adverse Events
  U.S. National Institutes of Health, 2021
• Erythroderma is defined as erythema that covers more than 70% of the body surface area. It represents the maximum severity of various skin disorders. Diagnosis is by history and examination. Treatment includes supportive measures and topical care.
  Merck Manuals
  Merck & Co., Inc., 2025
• Exfoliative dermatitis, or erythroderma, is an erythematous, scaly dermatitis involving most, if not all, of the skin. See the image below.
  Medscape
  WebMD, 2025
• Exfoliative dermatitis, generalized redness and scaling of the skin that usually arises as a complication of a preexisting skin disease or of an allergy. More rarely, it may be indicative of a systemic disease, such as cancer of the lymphoid tissue. The onset of exfoliative dermatitis is gradual;...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2025