Biologically Active Substance
fibrinogen Audio
fi·brin·o·gen [ fahy-brin-uh-juhn ]
Brand Names:
Artiss; EVARREST; Evicel; Fibryga; Raplixa; RiaSTAP; TachoSil; Tisseel; Vistaseal
Effect:
Increased Coagulation Activity; Increased Coagulation Factor Concentration
May Treat:
Afibrinogenemia; Hemorrhage
Definitions related to fibrinogen:
  • A fibrillar protein present in blood plasma; it converts to fibrin during the process of blood clot formation.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A protein that helps stop bleeding by aiding in forming blood clots.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Fibrinogen is a soluble protein in the plasma that is broken down to fibrin by the enzyme thrombin to form clots. The reference range for the different fibrinogen tests are as follows: Fibrinogen antigen: 149-353 mg/dL Fibrinogen: 150-400 mg/dL Fibrinogen antigen/functional ratio: 0.
    Medscape
    WebMD, 2019
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.