Immunologic Factor
filgrastim
[ fil-gras-tim ]
Brand Names:
Granix; Neupogen; Nivestym; Zarxio
Effect:
Increased Granulocytic Cell Production
May Prevent:
Infections
May Treat:
Neutropenia
More Information:
Definitions related to filgrastim:
-
A colony-stimulating factor that stimulates the production of neutrophils (a type of white blood cell). It is a cytokine that is a type of hematopoietic (blood-forming) agent.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
-
A recombinant granulocyte colony-stimulating factor (G-CSF) that is used in the treatment and prevention of NEUTROPENIA, preparation and collection of blood progenitor cells, and for use in PERIPHERAL BLOOD STEM CELL TRANSPLANTATION.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
-
A recombinant, non-glycosylated cytokine which is chemically identical to or similar to the endogenous cytokine human granulocyte colony-stimulating factor (G-CSF) isoform B, with immunomodulating activity. Filgrastim binds to and activates G-CSF receptors with the same biological activity and stability as the endogenous cytokine, thereby controlling the production, differentiation, and function of neutrophilic granulocyte progenitors.NCI ThesaurusU.S. National Cancer Institute, 2021
Return to OpenMD Medical Dictionary
> F
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.