Pharmacologic Substance
flurbiprofen
Brand Names:
Ansaid; Ocufen
Effect:
Decreased Prostaglandin Production
May Prevent:
Macular Edema; Miosis
May Treat:
Arthritis, Rheumatoid;
Inflammation;
Macular Edema;
Miosis;
Osteoarthritis
More Information:
Definitions related to flurbiprofen:
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A derivative of propionic acid, and a phenylalkanoic acid derivative of non-steroidal antiinflammatory drugs (NSAIDs) with analgesic, antiinflammatory and antipyretic effects. Flurbiprofen non-selectively binds to and inhibits cyclooxygenase (COX). This results in a reduction of arachidonic acid conversion into prostaglandins that are involved in the regulation of pain, inflammation and fever. This NSAID also inhibits carbonic anhydrase, thereby reducing the production of hydrogen and bicarbonate ions. Upon ocular administration, flurbiprofen may reduce bicarbonate ion concentrations leading to a decrease in the production of aqueous humor, thereby lowering intraocular pressure.NCI ThesaurusU.S. National Cancer Institute, 2021
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An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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