Biologically Active Substance
fusion protein
fu·sion pro·tein
Definitions related to fusion protein:
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A protein in which the coding region of two genes have become in-frame and co-continuous. Fusion proteins can be formed by chromosomal breakage and/or recombination and also can be experimentally created using recombinant DNA techniques.NCI ThesaurusU.S. National Cancer Institute, 2021
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A protein made from a fusion gene, which is created by joining parts of two different genes. Fusion genes may occur naturally in the body by transfer of DNA between chromosomes. For example, the BCR-ABL gene found in some types of leukemia is a fusion gene that makes the BCR-ABL fusion protein. Fusion genes and proteins can also be made in the laboratory by combining genes or parts of genes from the same or different organisms.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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(chimeric protein) Genetically engineered proteins created from fusion genes representing 2 or more proteins or species, such as toxins fused to cell-specific antibodies, or chromophores fused to DNA-binding proteins.CRISP ThesaurusNational Institutes of Health, 2006
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