Genetic Function
genomic imprinting
[ jee-nohm-ik im-prin-ting ]
Subclass of:
Epigenesis, Genetic
Definitions related to genomic imprinting:
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Inherently programmed modifications of the maternal and paternal genetic contributions to a zygote; leads to differentially expressed parental alleles during development and in adulthood; has been implicated as a cause of human disease.CRISP ThesaurusNational Institutes of Health, 2006
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Parent-specific expression or repression of genes or chromosomes in offspring.NCI ThesaurusU.S. National Cancer Institute, 2021
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The process by which one chromosome of a pair is chemically modified, depending on whether the chromosome comes from the father or the mother. These modifications lead to differential expression of a gene or genes on a maternally derived chromosome versus a paternally derived chromosome.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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The variable phenotypic expression of a GENE depending on whether it is of paternal or maternal origin, which is a function of the DNA METHYLATION pattern. Imprinted regions are observed to be more methylated and less transcriptionally active. (Segen, Dictionary of Modern Medicine, 1992)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Genomic imprinting, process wherein a gene is differentially expressed depending on whether it has been inherited from the mother or from the father. Such "parent-of-origin" effects are known to occur only in sexually reproducing placental mammals. Imprinting is one of a number of patterns of...Encyclopedia Britannica, Inc., 2020
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