Neoplastic Process
glioblastoma multiforme
[ glee-oh-blas-toh-muh mul-tih-form ]
Definitions related to glioblastoma multiforme:
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A tumor arising from glia in the central nervous system with macroscopic regions of necrosis and hemorrhage. Microscopically, glioblastoma multiforme is characterized by regions of pseudopalisading necrosis, pleomorphic nuclei and cells, and microvascular proliferation.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage and necrosis; may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways.CRISP ThesaurusNational Institutes of Health, 2006
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Glioblastoma multiforme (GBM) is by far the most common and most malignant of the glial tumors. Even with optimal therapy, median survival is only about 12 monthsWebMD, 2019
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