Pharmacologic Substance
granisetron hydrochloride Audio
[ gra-nih-seh-tron hy-droh-klor-ide ]
Effect:
Decreased Serotonin Activity; Emesis Suppression
May Prevent:
Postoperative Nausea and Vomiting
More Information:
ChemID; DailyMed; PDR
Definitions related to granisetron hydrochloride:
  • A drug used to treat nausea and vomiting caused by cancer treatment. It is a type of serotonin receptor antagonist and a type of antiemetic.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • The hydrochloride salt of an indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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