Cell
granulosa cell
Subclass of:
Ovarian Follicle;
Epithelial Cells;
Endocrine Cells
Definitions related to granulosa cell:
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Cells surrounding the vesicular ovarian follicle and forming the stratum granulosum and cumulus oophorus; after ovulation, they are transformed to lutein cells.CRISP ThesaurusNational Institutes of Health, 2006
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Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(ovarian granulosa cell) A cuboidal cell derived from a spindle-shaped granulosa cell precursor. Initially, ovarian granulosa cells create a single layer surrounding an oocyte. The oocyte and its single layer of ovarian granulosa cells make up a primary follicle. Proliferation of the ovarian granulosa cells leads to multiple cell layers surrounding the oocyte and maturation into a secondary follicle. The granulosa cells extend cytoplasmic processes to form gestational gap-junction-like unions with the plasma membrane of the oocyte. The continued growth of the ovarian granulosa cells takes the oocyte to the Graafian follicle stage. Once ovulation occurs, the granulosa cells become part of the corpus luteum. A major function of an ovarian granulosa cell is hormone production and secretion.NCI ThesaurusU.S. National Cancer Institute, 2021
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