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What is heart disease?
Mayo Clinic
Related terms:
cardiovascular disease
vascular diseases
cardiovascular infection
Disease or Syndrome
heart disease Audio
heart dis·ease [ hahrt dih-zeez ]
Subclass of:
Cardiovascular Diseases
Also called:
Cardiac diseases
Definitions related to heart diseases:
  • (heart disorder) A non-neoplastic or neoplastic disorder that affects the heart and/or the pericardium. Representative examples include endocarditis, pericarditis, atrial myxoma, cardiac myeloid sarcoma, and pericardial malignant mesothelioma.
    NCI
    U.S. National Cancer Institute, 2021
  • Heart disease is a general term that includes many types of heart problems. It's also called cardiovascular disease, which means heart and blood vessel disease. Heart disease is the leading cause of death in the United States, but there are ways to prevent and manage many types of heart disease. There are many different types of heart disease. Some you may be born with, called congenital heart disease. Other types develop during your lifetime. Coronary artery disease (also called coronary heart disease) is the most common type of heart disease. It happens slowly over time when a sticky substance called plaque builds up in the arteries that supply your heart muscle with blood. The plaque narrows or blocks blood flow to the heart muscle and can lead to other heart problems: Angina - chest pain from lack of blood flow; Heart attacks - when part of the heart muscle dies from loss of blood flow; Heart failure - when your heart can't pump enough blood to meet your body's needs; Arrhythmia - a problem with the rate or rhythm of your heartbeat. Other types of heart diseases may affect your heart valves or heart muscle (cardiomyopathy). The causes of heart disease depend on the type of disease. Some possible causes include lifestyle, genetics, infections, medicines, and other diseases. There are many different factors that can make you more likely to develop heart disease. Some of these factors you can change, but others you cannot. Age. Your risk of heart disease goes up as you get older.; Sex. Some factors may affect heart disease risk differently in women than in men.; Family history and genetics. A family history of early heart disease raises your risk of heart disease. And research has shown that some genes are linked to a higher risk of certain heart diseases.; Race/ethnicity. Certain groups have higher risks than others.; Lifestyle habits. Over time, unhealthy lifestyle habits can raise your risk heart disease: Eating a diet high in saturated fats, refined carbohydrates, and salt.; Not getting enough physical activity.; Drinking too much alcohol.; Smoking and exposure to secondhand smoke.; Too much stress.; Having other medical conditions can raise your risk of heart diseases. These conditions include: High blood pressure.; High cholesterol levels.; Diabetes.; Obesity.; Autoimmune and inflammatory diseases.; Chronic kidney disease.; Metabolic syndrome. . Your symptoms will depend on the type of heart disease you have. You may not have symptoms at first. In some cases, you may not know you have heart disease until you have a complication such as a heart attack. To find out if you have heart disease, your health care provider will: Ask about your medical history, including your symptoms; Ask about your family health history, including relatives who have had heart disease; Do a physical exam; Likely run...
    MedlinePlus
    U.S. National Library of Medicine, 2025
  • (heart disorder) Impairment of health or a condition of abnormal functioning of the heart.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Pathological conditions involving the HEART including its structural and functional abnormalities.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • (unspecified heart problem) The report describes a non-specific problem with the heart. Note: Please use "Appropriate Term / Code Not Available" if the report describes a specific problem but the relevant term does not exist.
    U.S. FDA Glossary
    U.S. Food & Drug Administration, 2021
  • Heart disease describes a range of conditions that affect your heart. Diseases under the heart disease umbrella include blood vessel diseases, such as coronary artery disease; heart rhythm problems (arrhythmias); and heart defects you're born with (congenital heart defects), among others.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
  • Heart disease, any disorder of the heart. Examples include coronary heart disease, congenital heart disease, and pulmonary heart disease, as well as rheumatic heart disease, hypertension, inflammation of the heart muscle (myocarditis) or of its inner or outer membrane...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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