Biologically Active Substance
heat shock protein
Subclass of:
Molecular Chaperones
Definitions related to heat shock proteins:
-
(stress protein) Family of highly conserved, specific proteins produced by prokaryotic and eukaryotic cells in response to heat shock or other stressor; some may protect other proteins from denaturation or degradation.CRISP ThesaurusNational Institutes of Health, 2006
-
A family of highly-conserved proteins that are synthesized in response to hyperthermia (heat shock), hypoxia, or other stresses that appear to increase cellular thermal tolerance and enable cells to recover from stress. Some heat shock proteins may protect other proteins from denaturation, degradation or perform functions essential to cell survival under these conditions.NCI ThesaurusU.S. National Cancer Institute, 2021
-
Any of a group of proteins that are synthesized in response to hyperthermia, hypoxia, or other stresses and that are believed to enable cells to recover from these stresses, perhaps by enabling recovery of gene expression; occur in prokaryotes and eukaryotes, and at least some proteins are similar in vertebrates and invertebrates.CRISP ThesaurusNational Institutes of Health, 2006
-
(heat-shock protein) One of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of oxygen or glucose (sugar). Heat-shock proteins help other proteins function in normal cells and may be present at high levels in cancer cells. Blocking the activity of a heat-shock protein called HSP90 is being studied in the treatment of cancer. Other heat-shock proteins including HSP70 and gp96 are being studied in vaccines to treat cancer.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
-
(heat-shock proteins) Proteins which are synthesized in eukaryotic organisms and bacteria in response to hyperthermia and other environmental stresses. They increase thermal tolerance and perform functions essential to cell survival under these conditions.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
Return to OpenMD Medical Dictionary
> H
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.