Neoplastic Process
Hemangiosarcoma

[ an-jee-oh-sahr-koh-muh ]
Subclass of:
Neoplasms, Vascular Tissue;
Sarcoma
Definitions related to hemangiosarcoma:
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(hemangiosarcoma, malignant) A malignant vascular neoplasm arising from endothelial cells.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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(angiosarcoma) A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma.NCI ThesaurusU.S. National Cancer Institute, 2021
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(angiosarcoma) A rare vascular tumor characterized by a malignant space-occupying lesion composed of cells variably recapitulating features of normal endothelium. It mostly develops as a cutaneous tumor and is much less frequently located in the deep soft tissue. Clinical presentation is an enlarging mass, sometimes with symptoms like coagulopathy, anemia, persistent hematoma, or bruisability. Some tumors are associated with pre-existing conditions, e. g. Klippel-Trenaunay syndrome, Maffucci syndrome, or following radiation, among others. Older age, retroperitoneal location, large size, and high mitotic activity are predictors for poor outcome.OrphaNetINSERM, 2021
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(angiosarcoma) Malignant neoplasm arising from vascular endothelial cells; the term may denote a specific histologic subtype, usually hemangiosarcoma, but also others such a lymphangiosarcoma or hemangiopericytoma.CRISP ThesaurusNational Institutes of Health, 2006
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A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A type of cancer that begins in the cells that line blood vessels.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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An angiosarcoma (AS) is an uncommon malignant neoplasm characterized by rapidly proliferating, extensively infiltrating anaplastic cells derived from blood vessels and lining irregular blood-filled spaces. Specialists apply the term angiosarcoma to a wide range of malignant endothelial vascular neoplasms that affect a variety of sites.WebMD, 2019
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Angiosarcoma is a rare type of cancer that forms in the lining of the blood vessels and lymph vessels. Your lymph vessels, which are part of your immune system, collect bacteria, viruses and waste products from your body and dispose of them.Mayo Foundation for Medical Education and Research
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