Pharmacologic Substance
hematoporphyrin derivative
[ hee-muh-toh-por-fih-rin deh-rih-vuh-tiv ]
Subclass of:
Hematoporphyrins
Definitions related to hematoporphyrin derivative:
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A complex mixture of monomeric and aggregated porphyrins with photosensitizing activity. Upon systemic administration, hematoporphyrin derivatives accumulate in tumor cells and, once activated by red laser light (630 nm), in the presence of oxygen, produce singlet oxygen and other reactive oxygen radicals, resulting in local radical-mediated tumor cell death.NCI ThesaurusU.S. National Cancer Institute, 2021
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A drug used in photodynamic therapy that is absorbed by tumor cells. When exposed to light, it becomes active and kills the cancer cells.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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