• (hepatoblastoma, malignant) A malignant liver neoplasm composed of immature hepatocytic elements.
  CDISC Terminology
  Clinical Data Interchange Standards Consortium (CDISC), 2021
• A kind of neoplasm of the liver that originates from immature liver precursor cells and macroscopically is composed of tissue resembling fetal or mature liver cells or bile ducts.
  Human Phenotype Ontology (HPO)
  The Human Phenotype Ontology Project, 2025
• A malignant embryonal neoplasm that arises from the liver. It occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Microscopically, it consists of either epithelial or epithelial and mesenchymal components.
  NCI
  U.S. National Cancer Institute, 2021
• A malignant liver tumor that arises from precursors of hepatocytes. It occurs almost exclusively in infants. The lungs are the most common site of metastasis.
  NICHD Pediatric Terminology
  U.S. National Cancer Institute, 2021
• A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025
• A type of liver tumor that occurs in infants and children.
  NCI Dictionary of Cancer Terms
  U.S. National Cancer Institute, 2021
• Malignant liver neoplasm occurring in children and composed of tissue resembling fetal or mature liver cells or bile ducts.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Hepatoblastoma is the most common liver cancer in children, although it is relatively uncommon compared with other solid tumors in the pediatric age group. Over the past several years, pathologic variations of hepatoblastoma have been identified, and techniques for establishing the diagnosis of childhood hepatic tumors have improved.
  Medscape
  WebMD, 2025
• Hepatoblastoma is a rare malignant (cancerous) tumor of the liver that usually occurs in the first 3 years of life. In early stages of the condition, there may be no concerning signs or symptoms. As the tumor gets larger, affected children may experience a painful, abdominal lump; swelling of the abdomen; unexplained weight loss; loss of...
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences