Neoplastic Process
nephroblastoma
Subclass of:
Neoplastic Syndromes, Hereditary;
Neoplasms, Complex and Mixed;
Kidney Neoplasm
Also called:
Wilms Tumor; Wilms' Tumor
Definitions related to nephroblastoma:
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(nephroblastoma, malignant) A malignant embryonal neoplasm of the kidney.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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(wilms tumor) A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(wilms tumor) An embryonal neoplasm characterized by the presence of epithelial, mesenchymal, and blastema components. The vast majority of cases arise from the kidney. A small number of cases with morphologic features resembling Wilms tumor of the kidney have been reported arising from the ovary and the cervix.NCI ThesaurusU.S. National Cancer Institute, 2021
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(wilms tumor) Wilms tumor is a rare type of kidney cancer. It causes a tumor on one or both kidneys. It usually affects children, but can happen in adults. Having certain genetic conditions or birth defects can increase the risk of getting it. Children that are at risk should be screened for Wilms tumor every three months until they turn eight. Symptoms include a lump in the abdomen, blood in the urine, and a fever for no reason. Tests that examine the kidney and blood are used to find the tumor. Doctors usually diagnose and remove the tumor in surgery. Other treatments include chemotherapy and radiation and biologic therapies. Biologic therapy boosts your body's own ability to fight cancer. NIH: National Cancer InstituteMedlinePlusU.S. National Library of Medicine, 2021
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(wilms' tumor) A disease in which malignant (cancer) cells are found in the kidney, and may spread to the lungs, liver, or nearby lymph nodes. Wilms tumor usually occurs in children younger than 5 years old.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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(wilms' tumor) Pediatric nephroblastoma originating from embryonic kidney stem cells; usually affects children before the fifth year, but may occur in the fetus or rarely in later life; caused by defects in one or more tumor suppressor genes.CRISP ThesaurusNational Institutes of Health, 2006
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A malignant neoplasm of embryonal origin arising within the kidney.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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Malignant kidney tumor made up of three cell types: blastemal, stromal, and epithelial, but not all present in every case.CRISP ThesaurusNational Institutes of Health, 2006
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The presence of a nephroblastoma, which is a neoplasm of the kidney that primarily affects children.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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(kidney wilms tumor) An embryonal pediatric tumor of the kidney which may also be seen rarely in adults. The peak incidence of Wilms tumor is between the second and fifth year of life. Microscopically, it is composed of a mixture of cellular elements (blastemal, stromal, and epithelial). The most common sites of metastasis include the regional lymph nodes, lungs, and liver.NCI ThesaurusU.S. National Cancer Institute, 2021
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Wilms tumor is an embryonal cancer of the kidney composed of blastemal, stromal, and epithelial elements. Genetic abnormalities have been implicated in the pathogenesis, but familial inheritance accounts for only 1 to 2% of cases. Diagnosis is by ultrasonography, abdominal CT, or MRI. Treatment may include surgical resection,...Merck & Co., Inc., 2020
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Wilms tumor, or nephroblastoma, is the most common childhood abdominal malignancy. The median age at diagnosis of Wilms tumor is approximately 3.WebMD, 2019
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Wilms' tumor is a rare kidney cancer that primarily affects children. Also known as nephroblastoma, it's the most common cancer of the kidneys in children. Wilms' tumor most often affects children ages 3 to 4 and becomes much less common after age 5.Mayo Foundation for Medical Education and Research
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A rare malignant renal tumor, typically affecting the pediatric population, characterized by an abnormal proliferation of cells that resemble the kidney cells of an embryo (metanephroma), leading to the term embryonal tumor.National Center for Advancing Translational Sciences
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Wilms tumor, or nephroblastoma, is the most common form of renal malignancy in childhood. It usually occurs in the first 2 to 5 years of life. Approximately 500 children and adolescents <20 years of age are diagnosed each year in the US. The risk for developing Wilms tumor is increased in certain congenital overgrowth syndromes,...Athenahealth, Inc., 2019
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Nephroblastoma, malignant renal (kidney) tumour of early childhood. In 75 percent of the cases, the tumour grows before the age of five; about two-thirds of the instances are apparent by two years of age. The tumour grows rapidly and can approach the weight of the rest of the body...Encyclopedia Britannica, Inc., 2020
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