Neoplastic Process
hepatocellular carcinoma
[ hep-uh-toh-sel-yuh-ler, hi-pat-oh- kahr-suh-noh-muh ]
Subclass of:
Liver neoplasms;
Adenocarcinoma
Also called:
Hepatocellular Carcinoma; Hepatoma
Definitions related to liver carcinoma:
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(carcinoma, hepatocellular, malignant) A malignant neoplasm arising from hepatocytes.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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(hepatocellular carcinoma) A kind of neoplasm of the liver that originates in hepatocytes and presents macroscopically as a soft and hemorrhagic tan mass in the liver.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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(hepatocellular carcinoma) A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation.NCI ThesaurusU.S. National Cancer Institute, 2021
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(hepatocellular carcinoma) A type of adenocarcinoma and the most common type of liver tumor.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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(hepatocellular carcinoma) Primary malignant neoplasm of epithelial liver cells; it ranges from a well-differentiated tumor with epithelial cells indistinguishable from normal hepatocytes to a poorly differentiated neoplasm; the cells may be uniform or markedly pleomorphic, or form giant cells; associations exist with chronic hepatitis B virus infection, some types of cirrhosis, and hepatitis C virus infection.CRISP ThesaurusNational Institutes of Health, 2006
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(carcinoma, hepatocellular) A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Hepatocellular carcinoma usually occurs in patients with cirrhosis and is common in areas where infection with hepatitis B and C viruses is prevalent. Symptoms and signs are usually nonspecific. Diagnosis is based on alpha-fetoprotein (AFP) levels, imaging tests, and sometimes liver biopsy. Screening with periodic AFP measurement and...Merck & Co., Inc., 2020
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Hepatocellular carcinoma (HCC) is a primary malignancy of the liver. Hepatocellular carcinoma is now the third leading cause of cancer deaths worldwide, with over 500,000 people affected.WebMD, 2019
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Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. Hepatocellular carcinoma occurs most often in people with chronic liver diseases, such as cirrhosis caused by hepatitis B or hepatitis C infection.Mayo Foundation for Medical Education and Research
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Hepatoma (also known as hepatocellular carcinoma) is a primary cancer arising from hepatocytes in predominantly cirrhotic liver. However, some patients may not have cirrhosis before developing hepatoma, especially patients with chronic hepatitis B virus.Athenahealth, Inc., 2019
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