A cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell. The two major types of Hodgkin lymphoma are classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats.

A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.

Hodgkin lymphoma, also called Hodgkin disease, is a type of cancer that develops in the lymph system. Your lymph system is part of your immune system. It helps protect your body from infection and disease. The lymph system is made up of tissues and organs that produce, store, and carry white blood cells. It includes your: Bone marrow; Lymph nodes; Lymphatic vessels; Spleen; Thymus; Tonsils. Hodgkin lymphoma is one of the main types of lymphoma. The other is non-Hodgkin lymphoma. Each type starts in different types of white blood cells. The cause of Hodgkin lymphoma is unknown. But there are certain people who are at higher risk of developing it. Certain factors can make you more likely to develop Hodgkin lymphoma: Age. Hodgkin lymphoma is most common in early adulthood (age 20-39 years) and in late adulthood (age 65 years and older).; Being male. The risk of adult Hodgkin lymphoma is slightly higher in males than in females.; Past Epstein-Barr virus (EBV) infection. Having an infection with EBV as a young child or teenager increases your risk of Hodgkin lymphoma.; A family history of Hodgkin lymphoma. Having a parent or sibling with Hodgkin lymphoma increases your risk of developing it. The signs and symptoms of Hodgkin lymphoma may include: Painless, swollen lymph nodes in the neck, underarm, or groin; Fever for no known reason; Drenching night sweats (very heavy sweating during sleep); Weight loss for no known reason in the past 6 months; Itchy skin, especially after bathing or drinking alcohol; Fatigue. To find out if you have Hodgkin lymphoma, your provider: Will ask about your symptoms and medical history. This will include checking for signs of disease, such as lumps or anything else that seems unusual.; May order some lab tests, such as: Complete blood count; Blood chemistry studies; Lactate dehydrogenase (LDH) test; Erythrocyte sedimentation rate (ESR) test; Blood tests to rule out other medical conditions; May do imaging tests such as a CT and PET (positron emission tomography) scans; May do a lymph node biopsy. . Treatments for Hodgkin lymphoma include: Chemotherapy; Radiation therapy; Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells; Cancer immunotherapy. Hodgkin lymphoma can usually be cured if it is found and treated early. NIH: National Cancer Institute

(hodgkin lymphoma) A lymphoma characterized by the presence of relatively few malignant cells called Reed-Sternberg cells and mononuclear Hodgkin cells that are admixed with nonneoplastic inflammatory cells. The malignant cells have a distinctive immunophenotype; they are positive for CD30 and CD15 and negative for CD3, CD20, and CD45.

(hodgkin lymphoma) A malignant neoplasm of the lymphatic system that is comprised of abnormal lymphocytes and is characterized by the presence of Reed-Sternberg cells.

(hodgkin lymphoma) A type of lymphoma characterized microscopically by multinucleated Reed-Sternberg cells.

(hodgkin's disease) Malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue, and the presence of large, usually multinucleate, cells (Reed-Sternberg cells) of unknown origin.

(hodgkin's granuloma) An obsolete term that refers to cases of Hodgkin lymphoma excluding cases that were classified as Hodgkin's paragranuloma and Hodgkin's sarcoma.

(hodgkin's paragranuloma) An obsolete term that includes cases currently classified as nodular lymphocyte predominant Hodgkin lymphoma.

Hodgkin lymphoma is a localized or disseminated malignant proliferation of cells of the lymphoreticular system, primarily involving lymph node tissue, spleen, liver, and bone marrow. Symptoms typically include painless lymphadenopathy, sometimes with fever, night sweats, unintentional weight loss, pruritus, splenomegaly, and...

Hodgkin lymphoma (formerly, Hodgkin disease) is a potentially curable lymphoma with distinct histology, biologic behavior, and clinical characteristics. The disease is defined in terms of its microscopic appearance (histology) (see the image below) and the expression of cell surface markers (immunophenotype).

Hodgkin's lymphoma - formerly known as Hodgkin's disease - is a cancer of the lymphatic system, which is part of your immune system. It may affect people of any age, but is most common in people between 20 and 40 years old and those over 55.

Hodgkin lymphoma (HL) is a heterogeneous group of malignant lymphoid neoplasms of B- cell origin characterized histologically by the presence of Hodgkin and Reed-Sternberg (HRS) cells in the vast majority of cases.

Hodgkin lymphoma (HL), also referred to as Hodgkin disease, is an uncommon hematologic malignancy arising from mature B cells. It is characterized by the presence of Hodgkin cells and Reed-Sternberg cells.

Hodgkin lymphoma, an uncommon cancer of the lymphatic system (malignant lymphoma) that usually strikes young adults and people 55 years of age or older. Most patients can be cured if the disease is detected in its early stages, but even those with advanced Hodgkin lymphoma have a significant chance...