Cell
hybridoma
[ hahy-bri-doh-muh ]
Subclass of:
Hybrid Cells;
Clone Cells
Definitions related to hybridomas:
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A tumor of hybrid cells used in the in vitro production of specific monoclonal antibodies; produced by fusion of an established tissue culture line of lymphocyte tumor cells (e.g., mouse plasmacytoma cells) and specific antibody-producing cells (e.g., splenocytes from specifically immunized mice); fusions are accomplished by use of polyethylene glycol or other methods.NCI ThesaurusU.S. National Cancer Institute, 2021
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Cells artificially created by fusion of activated lymphocytes with neoplastic cells; the resulting hybrid cells are cloned and produce pure or monoclonal antibodies or T-cell products, identical to those produced by the immunologically competent parent, and continually grow and divide as the neoplastic parent.CRISP ThesaurusNational Institutes of Health, 2006
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