Pharmacologic Substance
hydrochlorothiazide
[ hahy-druh-klawr-uh-thahy-uh-zahyd, -klohr- ]
Brand Names:
Accuretic; Aldactazide; Atacand HCT; Avalide; Benicar HCT; Diovan HCT; Dutoprol; Dyazide; Exforge HCT; Hyzaar; Lopressor HCT; Lotensin HCT; Maxzide; Micardis-HCT; Microzide; Prinzide; Tekturna HCT; Teveten HCT; Tribenzor; Uniretic; Vaseretic; Zestoretic; Ziac
Effect:
Decreased Blood Pressure; Decreased Distal Tubule Ca++ Excretion; Decreased Intravascular Volume; Increased Distal Tubule Cl- Excretion; Increased Distal Tubule H+ Excretion; Increased Distal Tubule K+ Excretion; Increased Distal Tubule Na+ Excretion; Increased Diuresis; Vasodilation
May Treat:
Edema;
Heart Failure;
Hypertension;
Nephrotic Syndrome
More Information:
Definitions related to hydrochlorothiazide:
-
A short acting thiazide diuretic. Hydrochlorothiazide (HCTZ) is widely used to treat hypertension and edema. This agent's metabolite appears to preferentially bind to and accumulate in red blood cells. This agent is primarily excreted by the kidneys.NCI ThesaurusU.S. National Cancer Institute, 2021
-
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
Return to OpenMD Medical Dictionary
> H
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.