Pharmacologic Substance
hydrocodone
[ hahy-druh-koh-dohn ]
Brand Names:
Bromplex HD; B-Tuss; De-Chlor G; De-Chlor HC; De-Chlor MR; De-Chlor NX; Hycet; Hycodan; Hycofenix; Hydro GP; Hydromet; Hydron CP; Hydron EX; Hydron KGS; Hydro-PC II; Hy-KXP; Hysingla; Ibudone; KGS HC; Lorcet; Lortab; Nariz HC; Nazarin HC; Norco; Obredon; Prolex DH; P-V-Tussin; Relasin HC; Reprexain; Simuc-HD; Su-Tuss HD; Triant-HC; TussiCaps; Tussigon; Tussionex; Ventuss; Verdrocet; Vicodin; Vicoprofen; Xylon; Zamicet; Zohydro
Effect:
Analgesia; Decreased Medullary Respiratory Drive; Decreased Organized Electrical Activity
May Treat:
Cough; Lung Diseases, Obstructive; Pain, Postoperative
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to hydrocodone:
  • A semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6.
    NCI
    U.S. National Cancer Institute, 2021
  • Narcotic analgesic related to CODEINE, but more potent and more addicting by weight. It is used also as cough suppressant.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.