Disease or Syndrome
hypercalcemia Audio
[ hahy-per-kal-see-mee-uh ]
Subclass of:
Calcium Metabolism Disorders; Water-Electrolyte Imbalance
Etymology:
Greek hyper = excess + Latin calx = chalk (calcium) + Greek haima = blood + -ia = condition
Definitions related to hypercalcemia:
  • Abnormally high concentration of calcium in the peripheral blood.
    NCI
    U.S. National Cancer Institute, 2021
  • Abnormally high level of calcium in the blood; manifestations include fatigability, muscle weakness, depression, anorexia, nausea, and constipation.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • An abnormally increased calcium concentration in the blood.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Higher than normal levels of calcium in the blood. Some types of cancer increase the risk of hypercalcemia.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium (corrected for albumin) in blood.
    Common Terminology Criteria for Adverse Events
    U.S. National Institutes of Health, 2021
  • Hypercalcemia is a total serum calcium concentration > 10.4 mg/dL (> 2.60 mmol/L) or ionized serum calcium > 5.2 mg/dL (> 1.30 mmol/L). Principal causes include hyperparathyroidism, vitamin D toxicity, and cancer. Clinical features include polyuria, constipation, muscle weakness, confusion, and coma. Diagnosis is by measuring serum...
    Merck Manuals
    Merck & Co., Inc., 2025
  • Hypercalcemia is a total serum calcium concentration > 10.4 mg/dL (> 2.60 mmol/L) or ionized serum calcium > 5.2 mg/dL (> 1.30 mmol/L). Principal causes include hyperparathyroidism, vitamin D toxicity, and cancer. Clinical features include polyuria, constipation, muscle weakness, confusion, and coma. Diagnosis is by measuring serum...
    Merck Manuals
    Merck & Co., Inc., 2025
  • Hypercalcemia can result when too much calcium (Ca) enters the extracellular fluid (ECF) or when there is insufficient calcium excretion from the kidneys. Calcium plays an important role in intracellular and extracellular metabolism controlling such processes as nerve conduction, muscle contraction, coagulation, electrolyte and enzyme...
    Medscape
    WebMD, 2025
  • Hypercalcemia is a condition in which the calcium level in your blood is above normal. Too much calcium in your blood can weaken your bones, create kidney stones, and interfere with how your heart and brain work.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
Try this search on: Farlex, Merriam-Webster, Oxford Dictionary, or Wordnik

This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.