Disease or Syndrome
hyperkeratosis
hy·per·ker·a·to·sis [ hahy-per-ker-uh-toh-sis ]
Etymology:
Greek hyper = excessive + keras = horn + -osis = condition
Definitions related to hyperkeratosis:
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A condition marked by thickening of the outer layer of the skin, which is made of keratin (a tough, protective protein). It can result from normal use (corns, calluses), chronic inflammation (eczema), or genetic disorders (X-linked ichthyosis, ichthyosis vulgaris).NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Hyperkeratosis is thickening of the outer layer of the skin, the stratum corneum, which is composed of large, polyhedral, plate-like envelopes filled with keratin which are the dead cells that have migrated up from the stratum granulosum.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Hypertrophy of the outermost layer of the epidermis. It may be caused by physical or chemical irritants, irradiation, infection, or neoplastic processes.NCI ThesaurusU.S. National Cancer Institute, 2021
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Thickening of the outermost layer of stratified squamous epithelium.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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A disorder characterized by a thickening of the outer layer of the skin.Common Terminology Criteria for Adverse EventsU.S. National Institutes of Health, 2021
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