• A condition of diminution or cessation of secretion of one or more hormones from the anterior pituitary gland. This may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions.
  NCI
  U.S. National Cancer Institute, 2021
• Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including luteinizing hormone, follicle stimulating hormone, somatotropin; and corticotropin); may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Subnormal concentration of two or more pituitary hormones.
  NICHD Pediatric Terminology
  U.S. National Cancer Institute, 2021
• A disorder characterized by a decrease in production of hormones from the pituitary gland.
  Common Terminology Criteria for Adverse Events
  U.S. National Institutes of Health, 2021
• Hypopituitarism is an underactive pituitary gland that results in deficiency of one or more pituitary hormones. Symptoms of hypopituitarism depend on what hormone is deficient and may include short height, infertility, intolerance to cold, fatigue, and an inability to produce breast milk.
  Merck Manuals
  Merck & Co., Inc., 2025
• Hypopituitarism is a rare disorder in which your pituitary gland fails to produce one or more hormones, or doesn't produce enough hormones.
  Mayo Clinic
  Mayo Foundation for Medical Education and Research, 2025
• Hypopituitarism occurs when the body has low levels of certain hormones made by the pituitary gland. The pituitary gland normally makes several hormones (including growth hormone, thyroid stimulating hormone, adrenocorticotropic hormone, prolactin, follicle stimulating hormone and luteinizing hormone, vasopressin, and oxytocin). These...
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences
• Hypopituitarism refers to the partial or complete deficiency of one or more pituitary hormones. It may arise as a congenital defect during the development of the pituitary gland or as a result of acquired diseases of the pituitary gland, the parasellar structures, or the hypothalamus.
  Epocrates
  Athenahealth, Inc., 2019
• Hypopituitarism, deficiency of pituitary hormones caused by damage to the pituitary gland. Patients may have a deficiency of one or all pituitary hormones, including vasopressin (antidiuretic hormone), the hormone of the posterior pituitary gland that controls the excretion of urine. Deficiency of...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2025