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Diabetes Insipidus
A. Hasudungan
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Understanding Diabetes Insipidus
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Related terms:
anuria
diabetic nephropathy
Hepatorenal syndrome
hydronephrosis
hyperoxaluria
hyperpituitarism
renal hypertension
hypopituitarism
nephropathy
Disease or Syndrome
diabetes insipidus Audio
di·a·be·tes in·sip·i·dus [ dahy-uh-bee-tis, -teez ]
Subclass of:
Pituitary Diseases; Kidney Diseases
Also called:
DI
Definitions related to diabetes insipidus:
  • A condition characterized by excretion of large amounts of dilute urine, accompanied by excessive thirst. Causes include deficiency of antidiuretic hormone or failure of the kidneys to respond to antidiuretic hormone.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A disorder characterized by excretion of large amounts of urine, accompanied by excessive thirst. Causes include deficiency of antidiuretic hormone or failure of the kidneys to respond to antidiuretic hormone. It may also be drug-related.
    NCI
    U.S. National Cancer Institute, 2021
  • A state of excessive water intake and hypotonic (dilute) polyuria. Diabetes insipidus may be due to failure of vasopressin (AVP) release (central or neurogenic diabetes insipidus) or to a failure of the kidney to respond to AVP (nephrogenic diabetes insipidus).
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Diabetes insipidus (DI) causes frequent urination. You become extremely thirsty, so you drink. Then you urinate. This cycle can keep you from sleeping or even make you wet the bed. Your body produces lots of urine that is almost all water. DI is different from diabetes mellitus (DM), which involves insulin problems and high blood sugar. The symptoms can be similar. However, DI is related to how your kidneys handle fluids. It's much less common than DM. Urine and blood tests can show which one you have. Usually, DI is caused by a problem with your pituitary gland or your kidneys. Treatment depends on the cause of the problem. Medicines can often help. NIH: National Institute of Diabetes and Digestive and Kidney Diseases
    MedlinePlus
    U.S. National Library of Medicine, 2025
  • Metabolic disorder due to injury of the neurohypophyseal system; results in deficient quanity of antidiuretic hormone being released or produced, failure of tubular reabsorption of water in the kidney.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Diabetes insipidus (DI) is defined as the passage of large volumes (>3 L/24 hr) of dilute urine (< 300 mOsm/kg). It has the following 2 major forms: Central (neurogenic, pituitary, or neurohypophyseal) DI, characterized by decreased secretion of antidiuretic hormone (ADH; also referred to as arginine vasopressin [AVP]) Nephrogenic DI,...
    Medscape
    WebMD, 2025
  • Diabetes insipidus (die-uh-BEE-teze in-SIP-uh-dus) is an uncommon disorder that causes an imbalance of fluids in the body. This imbalance makes you very thirsty even if you've had something to drink. It also leads you to produce large amounts of urine.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
  • Diabetes insipidus (DI) is a metabolic disorder characterized by defective ability to concentrate urine in the kidneys, resulting in the production of large quantities of dilute urine. It may result from an absolute or relative deficiency of arginine vasopressin (AVP), also known as antidiuretic hormone (ADH), which is produced by the...
    Epocrates
    Athenahealth, Inc., 2019
  • Diabetes insipidus, pathological endocrine condition characterized by excessive thirst and excessive production of very dilute urine. The disorder is caused by a lack of antidiuretic hormone (vasopressin) or a blocking of its action. This hormone, produced by the hypothalamus, regulates the...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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